Glycine C2H5NO2 Properties,Formula,Price, Uses

What is Glycine

**Introduction to Glycine** Glycine is a simple, non-essential amino acid that plays a vital role in various biological processes. As the smallest amino acid, it serves as a building block for proteins and supports the synthesis of collagen, creatine, and glutathione. Glycine also acts as an inhibitory neurotransmitter in the central nervous system, promoting relaxation and improved sleep quality. Additionally, it aids in detoxification, digestive health, and muscle recovery. With its antioxidant and anti-inflammatory properties, glycine is widely used in dietary supplements, sports nutrition, and medical applications. Whether for cognitive function, metabolic health, or overall wellness, glycine is a versatile and beneficial compound for optimal body function.

Preparation Process: The preparation of glycine can be achieved through several methods: 1. **Strecker Synthesis**: React formaldehyde with ammonia and hydrogen cyanide to form aminoacetonitrile, which is then hydrolyzed to glycine. 2. **Hydrolysis of Gelatin or Collagen**: Heat gelatin or collagen with hydrochloric acid or sodium hydroxide to break peptide bonds, yielding glycine among other amino acids. 3. **Bucherer-Bergs Reaction**: Treat carbonyl compounds (e.g., formaldehyde) with ammonium carbonate and potassium cyanide, followed by hydrolysis to produce glycine. 4. **Enzymatic Synthesis**: Use microbial fermentation or immobilized enzymes (e.g., *E. coli*) to convert serine or glyoxylate into glycine. 5. **Electrochemical Synthesis**: Electrolyze a solution of chloroacetic acid and ammonia to form glycine. Each method varies in yield, purity, and scalability.

Usage Scenarios: Glycine is a non-essential amino acid with diverse applications. In medicine, it supports neurotransmission, muscle repair, and wound healing. It acts as an inhibitory neurotransmitter in the central nervous system, aiding sleep and cognitive function. In pharmaceuticals, glycine is used as a buffering agent in antacids and intravenous drugs. In cosmetics, it moisturizes and enhances skin elasticity. Industrially, it serves as a sweetener, preservative, and metal chelator in food processing. In agriculture, glycine improves plant growth and stress resistance. Additionally, it is utilized in biochemical research for protein synthesis and cell culture media. Its versatility makes it valuable across multiple fields.

Glycine Basic Info

Chemical Name Glycine

Synonyms Gly;H-GLY-OH;Gly-OH;Aminoacetic acid;L-Gly;BLOTTING BUFFER;TGC;GLYCINE USP;Glycine Amino acid;TT BUFFER

CAS No. 56-40-6

Molecular Formula C2H5NO2

Molecular Weight 75.07

PSA 63.32000

LogP -0.27000

Safely Info

RTECS MB7600000

Hazard Class -

Safety Statements 22-24/25

HS Code 29224910

WGK Germany 2

Packing Group -

RIDADR -

Risk Statements 33

Hazard Codes -

Caution Statement P261-P271-P280

Hazard Declaration H315-H319-H335

Symbol GHS07

Signal Word Warning

Glycine Price

Here is a rough price range for the chemical product "Glycine" in the 18 countries listed. Note that prices can vary based on purity, quantity, and market conditions:

- **United States**: $10–$30 per kg
- **China**: $5–$15 per kg
- **Russia**: $8–$20 per kg
- **Germany**: $12–$35 per kg
- **India**: $6–$18 per kg
- **Japan**: $15–$40 per kg
- **Brazil**: $10–$25 per kg
- **South Korea**: $12–$30 per kg
- **Philippines**: $8–$22 per kg
- **United Kingdom**: $12–$35 per kg
- **France**: $12–$35 per kg
- **Mexico**: $10–$25 per kg
- **Canada**: $10–$30 per kg
- **South Africa**: $8–$20 per kg
- **Egypt**: $7–$18 per kg
- **Turkey**: $8–$22 per kg
- **Thailand**: $7–$20 per kg
- **Indonesia**: $6–$18 per kg

If no specific price range is available for a country, it is marked as "No results." Let me know if you need further clarification!

MSDS

SECTION 1: Identification of the substance/mixture and of the company/undertaking
  Product identifiers
    Product name        : Glycine
    REACH No.        : A registration number is not available for this substance as the substance
    or its uses are exempted from registration, the annual tonnage does not
    require a registration or the registration is envisaged for a later
    registration deadline.
    CAS-No.        : 56-40-6
  Relevant identified uses of the substance or mixture and uses advised against
    Identified uses        : Laboratory chemicals, Manufacture of substances

SECTION 2: Hazards identification
  Classification of the substance or mixture
    Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
    This substance is not classified as dangerous according to Directive 67/548/EEC.
  Label elements
    The product does not need to be labelled in accordance with EC directives or respective national laws.
  Other hazards - none

SECTION 3: Composition/information on ingredients
  Substances
    Synonyms        : Aminoethanoic acid
    Aminoacetic acid
    Glycocoll
    Formula        : C2H5NO2
    Molecular Weight        : 75,07 g/mol
    CAS-No.        : 56-40-6
    EC-No.        : 200-272-2
    No components need to be disclosed according to the applicable regulations.

SECTION 4: First aid measures
  Description of first aid measures
  If inhaled
    If breathed in, move person into fresh air. If not breathing, give artificial respiration.
  In case of skin contact
    Wash off with soap and plenty of water.
  In case of eye contact
    Flush eyes with water as a precaution.
  If swallowed
    Never give anything by mouth to an unconscious person. Rinse mouth with water.
  Most important symptoms and effects, both acute and delayed
    The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
    section 11
  Indication of any immediate medical attention and special treatment needed
    no data available

SECTION 5: Firefighting measures
  Extinguishing media
  Suitable extinguishing media
    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  Special hazards arising from the substance or mixture
    Carbon oxides, nitrogen oxides (NOx), Ammonia
    Carbon oxides, nitrogen oxides (NOx)
  Advice for firefighters
    Wear self contained breathing apparatus for fire fighting if necessary.
  Further information
    no data available

SECTION 6: Accidental release measures
  Personal precautions, protective equipment and emergency procedures
    Avoid dust formation. Avoid breathing vapours, mist or gas.
    For personal protection see section 8.
  Environmental precautions
    Do not let product enter drains.
  Methods and materials for containment and cleaning up
    Sweep up and shovel. Keep in suitable, closed containers for disposal.
  Reference to other sections
    For disposal see section 13.

SECTION 7: Handling and storage
  Precautions for safe handling
    Provide appropriate exhaust ventilation at places where dust is formed.
    For precautions see section 2.2.
  Conditions for safe storage, including any incompatibilities
    Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
  Specific end use(s)
    A part from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection
  Control parameters
  Components with workplace control parameters
  Exposure controls
  Appropriate engineering controls
    General industrial hygiene practice.
  Personal protective equipment
  Eye/face protection
    Use equipment for eye protection tested and approved under appropriate government standards
    such as NIOSH (US) or EN 166(EU).
  Skin protection
    Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
    (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
    contaminated gloves after use in accordance with applicable laws and good laboratory practices.
    Wash and dry hands.
    The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
    the standard EN 374 derived from it.
    Full contact
    Material: Nitrile rubber
    Minimum layer thickness: 0,11 mm
    Break through time: 480 min
    Material tested:Dermatril® (KCL 740 / Z677272, Size M)
    Splash contact
    Material: Nitrile rubber
    Minimum layer thickness: 0,11 mm
    Break through time: 480 min
    Material tested:Dermatril® (KCL 740 / Z677272, Size M)
    data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300,     test method: EN374
    If used in solution, or mixed with other substances, and under conditions which differ from EN 374,
    contact the supplier of the CE approved gloves. This recommendation is advisory only and must
    be evaluated by an industrial hygienist and safety officer familiar with the specific situation of
    anticipated use by our customers. It should not be construed as offering an approval for any
    specific use scenario.
  Body Protection
    Choose body protection in relation to its type, to the concentration and amount of dangerous
    substances, and to the specific work-place., The type of protective equipment must be selected
    according to the concentration and amount of the dangerous substance at the specific workplace.
  Respiratory protection
    Respiratory protection is not required. Where protection from nuisance levels of dusts are desired,
    use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and
    approved under appropriate government standards such as NIOSH (US) or CEN (EU).
  Control of environmental exposure
    Do not let product enter drains.

SECTION 9: Physical and chemical properties
  Information on basic physical and chemical properties
    a) Appearance        Form: crystalline
    Colour: white
    b) Odour        no data available
    c) Odour Threshold        no data available
    d) pH        no data available
    e) Melting point/freezing        Melting point/range: 240 °C
    point
    f) Initial boiling point and no data available
    boiling range
    g) Flash point        no data available
    h) Evapouration rate        no data available
    i) Flammability (solid, gas) no data available
    j) Upper/lower        no data available
    flammability or
    explosive limits
    k) Vapour pressure        no data available
    l) Vapour density        no data available
    m) Relative density        no data available
    n) Water solubility        no data available
    o) Partition coefficient: n- no data available
    octanol/water
    p) Auto-ignition        no data available
    temperature
    q) Decomposition        no data available
    temperature
    r) Viscosity        no data available
    s) Explosive properties        no data available
    t) Oxidizing properties        no data available
  Other safety information
    no data available

SECTION 10: Stability and reactivity
  Reactivity
    no data available
  Chemical stability
    Stable under recommended storage conditions.
  Possibility of hazardous reactions
    no data available
  Conditions to avoid
    no data available
  Incompatible materials
    Strong oxidizing agents
  Hazardous decomposition products
    Other decomposition products - no data available
    In the event of fire: see section 5

SECTION 11: Toxicological information
  Information on toxicological effects
  Acute toxicity
    LD50 Oral - rat - 7.930 mg/kg
  Skin corrosion/irritation
    no data available
  Serious eye damage/eye irritation
    no data available
  Respiratory or skin sensitisation
    no data available
  Germ cell mutagenicity
    no data available
  Carcinogenicity
    IARC:        No component of this product present at levels greater than or equal to 0.1% is identified as
    probable, possible or confirmed human carcinogen by IARC.
  Reproductive toxicity
    no data available
  Specific target organ toxicity - single exposure
    no data available
  Specific target organ toxicity - repeated exposure
    no data available
  Aspiration hazard
    no data available
  Additional Information
    RTECS: MB7600000
    To the best of our knowledge, the chemical, physical, and toxicological properties have not been
    thoroughly investigated.

SECTION 12: Ecological information
  Toxicity
    no data available
  Persistence and degradability
    no data available
  Bioaccumulative potential
    no data available
  Mobility in soil
    no data available
  Results of PBT and vPvB assessment
    PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
  Other adverse effects
    no data available

SECTION 13: Disposal considerations
  Waste treatment methods
  Product
    Offer surplus and non-recyclable solutions to a licensed disposal company.
  Contaminated packaging
    Dispose of as unused product.

SECTION 14: Transport information
  UN number
    ADR/RID: -        IMDG: -        IATA: -
  UN proper shipping name
    ADR/RID: Not dangerous goods
    IMDG: Not dangerous goods
    IATA:        Not dangerous goods
  Transport hazard class(es)
    ADR/RID: -        IMDG: -        IATA: -
  Packaging group
    ADR/RID: -        IMDG: -        IATA: -
  Environmental hazards
    ADR/RID: no        IMDG Marine pollutant: no        IATA: no
  Special precautions for user
    no data available

SECTION 15 - REGULATORY INFORMATION
N/A

SECTION 16 - ADDITIONAL INFORMATION
N/A

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1.Identification

1.1 GHS Product identifier

Product name	Glycine

1.2 Other means of identification

Product number	-
Other names	2-aminoacetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only. Processing Aids and Additives
Uses advised against	no data available

1.4 Supplier's details

Company	MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address	Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road, Xuhui District, Shanghai, China
Telephone	+86(21)64956998
Fax	+86(21)54365166

1.5 Emergency phone number

Emergency phone number	+86-400-6021-666
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Not classified.

2.2 GHS label elements, including precautionary statements

Pictogram(s)	No symbol.
Signal word	No signal word.
Hazard statement(s)	none
Precautionary statement(s)
Prevention	none
Response	none
Storage	none
Disposal	none

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name	Common names and synonyms	CAS number	EC number	Concentration
Glycine	Glycine	56-40-6	none	100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Absorption, Distribution and Excretion

Absorbed from the small intestine via an active transport mechanism.

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Extinguish fires with a dry chemical, carbon dioxide, foam, or halon extinguisher. A water spray may also be used.

5.2 Specific hazards arising from the chemical

LOW. Ignites at very high temperatures.

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Glycine irrigation should be stored at a temperature of 40 degrees C or less; freezing should be avoided. Glycine irrigation should not be heated to temperatures > 66 degrees C.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state	white to off-white crystalline powder
Colour	White crystals
Odour	Odorless
Melting point/ freezing point	240°C(dec.)(lit.)
Boiling point or initial boiling point and boiling range	206°C(lit.)
Flammability	no data available
Lower and upper explosion limit / flammability limit	no data available
Flash point	88°C(lit.)
Auto-ignition temperature	no data available
Decomposition temperature	no data available
pH	0.2 molar soln in water: 4.0
Kinematic viscosity	no data available
Solubility	In water:25 g/100 mL (25 ºC)
Partition coefficient n-octanol/water (log value)	no data available
Vapour pressure	no data available
Density and/or relative density	1.595
Relative vapour density	no data available
Particle characteristics	no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

An amino acid. A 0.2M aqueous solution has a pH of 4.0., so acts as a weak acid. Has characteristics of both acid and base.

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

STARTS TO DECOMP AT 233 DEG C

11.Toxicological information

Acute toxicity

Oral: no data available
Inhalation: no data available
Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

Toxicity to fish: no data available
Toxicity to daphnia and other aquatic invertebrates: no data available
Toxicity to algae: no data available
Toxicity to microorganisms: no data available

12.2 Persistence and degradability

no data available

12.3 Bioaccumulative potential

no data available

12.4 Mobility in soil

no data available

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: Not dangerous goods.

IMDG: Not dangerous goods.

IATA: Not dangerous goods.

14.2 UN Proper Shipping Name

ADR/RID: unknown

IMDG: unknown

IATA: unknown

14.3 Transport hazard class(es)

ADR/RID: Not dangerous goods.

IMDG: Not dangerous goods.

IATA: Not dangerous goods.

14.4 Packing group, if applicable

ADR/RID: Not dangerous goods.

IMDG: Not dangerous goods.

IATA: Not dangerous goods.

14.5 Environmental hazards

ADR/RID: no

IMDG: no

IATA: no

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name	Common names and synonyms	CAS number	EC number
Glycine	Glycine	56-40-6	none
European Inventory of Existing Commercial Chemical Substances (EINECS)			Listed.
EC Inventory			Listed.
United States Toxic Substances Control Act (TSCA) Inventory			Listed.
China Catalog of Hazardous chemicals 2015			Not Listed.
New Zealand Inventory of Chemicals (NZIoC)			Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS)			Listed.
Vietnam National Chemical Inventory			Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)			Listed.

16.Other information

Information on revision

Creation Date	Aug 12, 2017
Revision Date	Aug 12, 2017

Abbreviations and acronyms

CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%

References

IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.

Glycine Products
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Glycine Suppliers

Company Name

Business Type

Location

Details

Shandong Lanyuguang Chemical Industry Co., Ltd

Other

China Shandong Weifang

Request For Quotation

Tianjin Dongfang Import & Export Co., L

China Tianjin Districts

Request For Quotation

Arshine Group Co., Ltd.

China Hunan Changsha

Request For Quotation

Shandong Airuike Chemical Co., Ltd.

China Shandong Qingdao

Request For Quotation

Honour Enterprise Company Limited

China Fujian Xiamen

Request For Quotation

Shaanxi TNJONE Pharmaceutical Co., Ltd

China Shaanxi Xi'an

Request For Quotation

Zouping xingyu Import & Export Co., Ltd.

Request For Quotation

Xi'an Lanshan Biotechnology Co., Ltd.

China Shaanxi Xi'an

Request For Quotation

wuhan Bright Chemical CO.,LTD

China Hubei Wuhan

Request For Quotation

Hangzhou KieRay Chem Co.

China Zhejiang Hangzhou

Request For Quotation

Glycine

What is Glycine

Glycine Basic Info

Safely Info

Glycine Price

MSDS

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Glycine Suppliers

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