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Ceramides

CAS No.: 100403-19-8

Formula: C24H47NO3

Molecular Weight: 397.63488

Suppliers: All(0) China Suppliers(18) Products(20)

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What is Ceramides

**Introduction to Ceramides** Ceramides are naturally occurring lipids that play a vital role in maintaining the skin’s barrier function and retaining moisture. Found abundantly in the outermost layer of the skin, they help protect against environmental stressors, prevent dryness, and support overall skin health. As we age, ceramide levels decline, leading to weakened skin barriers, increased sensitivity, and signs of aging. Skincare products enriched with ceramides replenish these essential lipids, restoring hydration, improving elasticity, and soothing irritated skin. Ideal for all skin types—especially dry, sensitive, or mature skin—ceramide-infused creams, serums, and cleansers offer a powerful solution for achieving a healthier, more resilient complexion.

Preparation Process: Ceramides can be prepared through chemical synthesis or extraction from natural sources. **Chemical synthesis** involves the condensation of sphingosine (or phytosphingosine) with a fatty acid, often using N-hydroxysuccinimide (NHS) or dicyclohexylcarbodiimide (DCC) as coupling agents. Alternatively, **enzymatic synthesis** employs ceramide synthase to catalyze the acylation of sphingoid bases. **Natural extraction** involves isolating ceramides from yeast, plants (e.g., wheat germ), or animal tissues (e.g., bovine brain) via solvent extraction, followed by purification using column chromatography. Semi-synthetic methods combine natural sphingolipid hydrolysis (e.g., from sphingomyelin) with re-acylation. The process may include hydrogenation to stabilize unsaturated bonds.

Usage Scenarios: Ceramides are lipid molecules naturally found in the skin's outermost layer (stratum corneum), playing a crucial role in maintaining the skin barrier and preventing moisture loss. They help retain hydration, improve skin elasticity, and protect against environmental irritants. In skincare, synthetic or plant-derived ceramides are used in moisturizers, serums, and creams to repair damaged skin barriers, alleviate dryness, and reduce signs of aging. They are particularly beneficial for conditions like eczema, psoriasis, and sensitive skin. Additionally, ceramides support wound healing and enhance the effectiveness of other active ingredients by reinforcing the skin’s protective function. Their use extends to hair care, where they strengthen and smooth hair cuticles.

Ceramides Basic Info

Chemical Name Ceramides

Synonyms Ceramides NP;CeramideNP;Aqua Ceramide;Ceramide 3B;Ceramide W.S;Ceramide Powder;Einecs 309-560-3;Ceramides Mixture;CAPROYL SPHINGOSINE;Ceramdie

CAS No. 100403-19-8

Molecular Formula C24H47NO3

Molecular Weight 397.63488

PSA 0.00000

LogP 0.00000

Safely Info

RTECS -

Hazard Class -

Safety Statements -

HS Code -

WGK Germany -

Packing Group -

RIDADR -

Risk Statements -

Hazard Codes -

Caution Statement P264-P280-P305+P351+P338-P337+P313P

Hazard Declaration H319

Symbol GHS07

Signal Word Warning

Ceramides Price

United States: $20-50
China: $15-40
Russia: No results
Germany: $20-50
India: $10-30
Japan: $30-60
Brazil: $25-45
South Korea: $25-50
Philippines: $10-30
United Kingdom: $20-50
France: $20-50
Mexico: $15-40
Canada: $20-50
South Africa: $15-40
Egypt: $15-40
Turkey: $15-40
Thailand: $10-30
Indonesia: $10-30