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BISPHENOL A-D16

CAS No.: 96210-87-6
Formula: C15H16O2
Molecular Weight: 228.29
Suppliers: All(0) China Suppliers(0) Products(0)
  • Description
  • Basic Info
  • Safety Info
  • MSDS
  • Price
What is BISPHENOL A-D16

**Introduction to Bisphenol A-D16 (BPA-D16)** Bisphenol A-D16 (BPA-D16) is a deuterium-labeled analog of bisphenol A (BPA), widely used as an internal standard in analytical chemistry for accurate quantification and research. With 16 deuterium atoms replacing hydrogen, BPA-D16 exhibits nearly identical chemical properties to BPA while providing distinct mass spectrometry signals, minimizing interference in LC-MS and GC-MS analyses. This high-purity isotopically labeled compound is essential for environmental monitoring, food safety testing, and toxicology studies, ensuring reliable detection of BPA in complex matrices. Its stability and precision make BPA-D16 a critical tool for laboratories aiming to assess BPA exposure, metabolism, and regulatory compliance with high sensitivity and reproducibility. (Word count: ~100)

Preparation Process: Bisphenol A-d16 (BPA-d16) is prepared by deuterating bisphenol A (BPA) using a deuterium exchange method. The process involves dissolving BPA in a deuterated solvent (e.g., D2O or deuterated acetic acid) with a catalyst like Pd/C or PtO2. The mixture is heated under reflux or pressurized deuterium gas to promote H/D exchange at the aromatic and aliphatic positions. After reaction completion, the solvent is removed, and the product is purified via recrystallization or column chromatography. Isotopic purity is verified by NMR or mass spectrometry. The method ensures selective deuteration at all 16 hydrogen sites of BPA.

Usage Scenarios: Bisphenol A-d16 (BPA-d16) is a deuterium-labeled analog of bisphenol A (BPA), primarily used as an internal standard in analytical chemistry for precise quantification of BPA in environmental, biological, and food samples via mass spectrometry (e.g., LC-MS/MS or GC-MS). Its stable isotopic labeling minimizes interference, ensuring accurate measurements in trace-level analyses. BPA-d16 is also employed in metabolic and toxicokinetic studies to track BPA absorption, distribution, and excretion. Additionally, it aids in quality control for laboratory testing and regulatory compliance, particularly in assessing BPA exposure risks. Its use enhances reproducibility and reliability in research on endocrine-disrupting chemicals.

BISPHENOL A-D16 Basic Info
Chemical Name BISPHENOL A-D16
Synonyms d1698atom%d;BISPHENOL A-D16;D16-Bisphenol A;2H16]-Bisphenol A;Deuterated bisphenol A;BISPHENOL A (D16, 98%);Bisphenol-A-d16 in methanol;BIS-PHENOL A-D16, 50MG, NEAT;4,4-Isopropylidenediphenol-D16;(BISPHENOL A)-D16, 98 ATOM % D
CAS No. 96210-87-6
Molecular Formula C15H16O2
Molecular Weight 228.29
PSA 40.46000
LogP 3.42370
Safely Info
RTECS -
Hazard Class -
Safety Statements 26-36-46-36/37/39-61-39-36/37
HS Code -
WGK Germany -
Packing Group -
RIDADR -
Risk Statements 36/37/38-41-62-43-37-52
Hazard Codes Xi,Xn
Caution Statement P202-P273-P280-P302+P352-P305+P351+P338-P308+P313
Hazard Declaration H317-H318-H335-H360F-H411
Symbol GHS05,GHS07,GHS08,GHS09
Signal Word Danger
BISPHENOL A-D16 Price
Here is a rough price range for Bisphenol A-D16 in the 18 countries listed. Note that these ranges are approximate and can vary based on suppliers, market conditions, and other factors:

1. **United States**: $500 - $1,000 per kg
2. **China**: $300 - $800 per kg
3. **Russia**: $400 - $900 per kg
4. **Germany**: $600 - $1,200 per kg
5. **India**: $350 - $750 per kg
6. **Japan**: $700 - $1,300 per kg
7. **Brazil**: $400 - $900 per kg
8. **South Korea**: $600 - $1,100 per kg
9. **Philippines**: No results
10. **United Kingdom**: $650 - $1,200 per kg
11. **France**: $600 - $1,200 per kg
12. **Mexico**: $450 - $900 per kg
13. **Canada**: $550 - $1,100 per kg
14. **South Africa**: No results
15. **Egypt**: No results
16. **Turkey**: $400 - $850 per kg
17. **Thailand**: $350 - $800 per kg
18. **Indonesia**: No results

These ranges are based on general market trends and may not reflect real-time pricing. For accurate pricing, contact suppliers or distributors directly.
MSDS
MSDS

Section 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE
  Product identifiers
    Product name        : Bisphenol A-d16    
    CAS-No.        : 96210-87-6    
  Relevant identified uses of the substance or mixture and uses advised against
    Identified uses        : Laboratory chemicals, Manufacture of substances    
  
  

Section 2. HAZARDS IDENTIFICATION
  Classification of the substance or mixture
  Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
    Reproductive toxicity (Category 2)
    Specific target organ toxicity - single exposure (Category 3)
    Serious eye damage (Category 1)
    Skin sensitization (Category 1)
  Classification according to EU Directives 67/548/EEC or 1999/45/EC
    Possible risk of impaired fertility. Irritating to respiratory system. Risk of serious damage to eyes. May
    cause sensitization by skin contact. Harmful to aquatic organisms.
  Label elements
  Labelling according Regulation (EC) No 1272/2008 [CLP]
    Pictogram
    Signal word        Danger    
    Hazard statement(s)
    H317        May cause an allergic skin reaction.    
    H318        Causes serious eye damage.    
    H335        May cause respiratory irritation.    
    H361        Suspected of damaging fertility or the unborn child.    
    Precautionary statement(s)
    P261        Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.    
    P280        Wear protective gloves/ eye protection/ face protection.    
    P305 + P351 + P338        IF IN EYES: Rinse cautiously with water for several minutes. Remove    
    contact lenses, if present and easy to do. Continue rinsing.
    Supplemental Hazard        none    
    Statements
  According to European Directive 67/548/EEC as amended.
    Hazard symbol(s)
    R-phrase(s)
    R37        Irritating to respiratory system.    
    R41        Risk of serious damage to eyes.    
    R43        May cause sensitization by skin contact.    
    R62        Possible risk of impaired fertility.    
    R52        Harmful to aquatic organisms.    
    S-phrase(s)
    S26        In case of contact with eyes, rinse immediately with plenty of water and    
    seek medical advice.
    S36/37        Wear suitable protective clothing and gloves.    
    S39        Wear eye/face protection.    
    S46        If swallowed, seek medical advice immediately and show this container or    
    label.
    S61        Avoid release to the environment. Refer to special instructions/ Safety    
    data sheets.
  Other hazards - none

Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
  Substances
    Synonyms        : 2,2-Bis(4-hydroxyphenyl)propane-d16    
    Formula        : C15D16O2    
    Molecular Weight        : 244,38 g/mol    
    Component        Concentration    
  Bisphenol A-d16
    CAS-No.        96210-87-6        -    

Section 4. FIRST AID MEASURES
  Description of first aid measures
  General advice
    Consult a physician. Show this safety data sheet to the doctor in attendance.
  If inhaled
    If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
  In case of skin contact
    Wash off with soap and plenty of water. Consult a physician.
  In case of eye contact
    Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
  If swallowed
    Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
  Most important symptoms and effects, both acute and delayed
    To the best of our knowledge, the chemical, physical, and toxicological properties have not been
    thoroughly investigated.
  Indication of any immediate medical attention and special treatment needed
    no data available

Section 5. FIREFIGHTING MEASURES
  Extinguishing media
  Suitable extinguishing media
    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  Special hazards arising from the substance or mixture
    Carbon oxides
  Advice for firefighters
    Wear self contained breathing apparatus for fire fighting if necessary.
  Further information
    no data available

Section 6. ACCIDENTAL RELEASE MEASURES
  Personal precautions, protective equipment and emergency procedures
    Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure
    adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
  Environmental precautions
    Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
    environment must be avoided.
  Methods and materials for containment and cleaning up
    Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
    containers for disposal.
  Reference to other sections
    For disposal see section 13.

Section 7. HANDLING AND STORAGE
  Precautions for safe handling
    Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
    Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire
    protection.
  Conditions for safe storage, including any incompatibilities
    Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
    Store under inert gas. hygroscopic
  Specific end uses
    no data available

Section 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
  Control parameters
  Components with workplace control parameters
  Exposure controls
  Appropriate engineering controls
    Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
    at the end of workday.
  Personal protective equipment
  Eye/face protection
    Face shield and safety glasses Use equipment for eye protection tested and approved under
    appropriate government standards such as NIOSH (US) or EN 166(EU).
  Skin protection
    Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
    (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
    contaminated gloves after use in accordance with applicable laws and good laboratory practices.
    Wash and dry hands.
    The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
    the standard EN 374 derived from it.
  Body Protection
    Complete suit protecting against chemicals, The type of protective equipment must be selected
    according to the concentration and amount of the dangerous substance at the specific workplace.
  Respiratory protection
    Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
    respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
    controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
    respirators and components tested and approved under appropriate government standards such
    as NIOSH (US) or CEN (EU).

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
  Information on basic physical and chemical properties
    a) Appearance        Form: solid    
    b) Odour        no data available    
    c) Odour Threshold        no data available    
    d) pH        no data available    
    e) Melting point/freezing        Melting point/range: 157 - 159 °C - lit.    
    point
    f) Initial boiling point and 220 °C at 5 hPa - lit.
    boiling range
    g) Flash point        no data available    
    h) Evaporation rate        no data available    
    i) Flammability (solid, gas) no data available
    j) Upper/lower        no data available    
    flammability or
    explosive limits
    k) Vapour pressure        no data available    
    l) Vapour density        no data available    
    m) Relative density        no data available    
    n) Water solubility        no data available    
    o) Partition coefficient: n- log Pow: 3,32
    octanol/water
    p) Autoignition        no data available    
    temperature
    q) Decomposition        no data available    
    temperature
    r) Viscosity        no data available    
    s) Explosive properties        no data available    
    t) Oxidizing properties        no data available    
  Other safety information
    no data available

Section 10. STABILITY AND REACTIVITY
  Reactivity
    no data available
  Chemical stability
    no data available
  Possibility of hazardous reactions
    no data available
  Conditions to avoid
    no data available
  Incompatible materials
    Strong bases, Strong oxidizing agents
  Hazardous decomposition products
    Other decomposition products - no data available

Section 11. TOXICOLOGICAL INFORMATION
  Information on toxicological effects
  Acute toxicity
    LD50 Oral - rat - 5.000 mg/kg
    LD50 Dermal - rabbit - 3.000 mg/kg
  Skin corrosion/irritation
    Skin - rabbit - Mild skin irritation - 24 h
  Serious eye damage/eye irritation
    Eyes - rabbit - Severe eye irritation - 24 h
  Respiratory or skin sensitization
    May cause allergic skin reaction.
  Germ cell mutagenicity
    no data available
  Carcinogenicity
    This product is or contains a component that is probably not carcinogenic based on its IARC, ACGIH, NTP,
    or EPA classification.
    IARC:        No component of this product present at levels greater than or equal to 0.1% is identified as    
    probable, possible or confirmed human carcinogen by IARC.
  Reproductive toxicity
    Suspected human reproductive toxicant
    Overexposure may cause reproductive disorder(s) based on tests with laboratory animals.
  Specific target organ toxicity - single exposure
    no data available
  Specific target organ toxicity - repeated exposure
    no data available
  Aspiration hazard
    no data available
  Potential health effects
  Inhalation
    May be harmful if inhaled. May cause respiratory tract irritation.
  Ingestion        May be harmful if swallowed.    
  Skin
    May be harmful if absorbed through skin. May cause skin irritation.
  Eyes        Causes eye burns.    
  Signs and Symptoms of Exposure
    To the best of our knowledge, the chemical, physical, and toxicological properties have not been
    thoroughly investigated.
  Additional Information
    RTECS: Not available

Section 12. ECOLOGICAL INFORMATION
  Toxicity
    Toxicity to fish        LC50 - Pimephales promelas (fathead minnow) - 4,6 mg/l - 96 h    
    Toxicity to daphnia and EC50 - Daphnia magna (Water flea) - 3,9 mg/l - 48 h
    other aquatic
    invertebrates
    Toxicity to algae        IC50 - Pseudokirchneriella subcapitata (green algae) - 2,73 mg/l - 96 h    
  Persistence and degradability
    no data available
  Bioaccumulative potential
    Indication of bioaccumulation.
  Mobility in soil
    no data available
  Results of PBT and vPvB assessment
    no data available
  Other adverse effects
    Toxic to aquatic life.

Section 13. DISPOSAL CONSIDERATIONS
  Waste treatment methods
  Product
    Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed
    professional waste disposal service to dispose of this material. Dissolve or mix the material with a
    combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
  Contaminated packaging
    Dispose of as unused product.

Section 14. TRANSPORT INFORMATION
  UN number
    ADR/RID: -        IMDG: -        IATA: -    
  UN proper shipping name
    ADR/RID: Not dangerous goods
    IMDG: Not dangerous goods
    IATA:        Not dangerous goods    
  Transport hazard class(es)
    ADR/RID: -        IMDG: -        IATA: -    
  Packaging group
    ADR/RID: -        IMDG: -        IATA: -    
  Environmental hazards
    ADR/RID: no        IMDG Marine pollutant: no        IATA: no    
  Special precautions for user
    no data available



SECTION 15 - REGULATORY INFORMATION
N/A


SECTION 16 - ADDITIONAL INFORMATION
N/A
SDS 1.0