1.Identification

1.1 GHS Product identifier

1.2 Other means of identification

1.3 Recommended use of the chemical and restrictions on use

1.4 Supplier's details

1.5 Emergency phone number

2.Hazard identification

2.1 Classification of the substance or mixture

Organic peroxides, Type B

Eye irritation, Category 2

Skin sensitization, Category 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Danger
Hazard statement(s)	H241 Heating may cause a fire or explosion H319 Causes serious eye irritation H317 May cause an allergic skin reaction
Precautionary statement(s)
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P234 Keep only in original packaging. P235 Keep cool. P240 Ground and bond container and receiving equipment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P264 Wash ... thoroughly after handling. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace.
Response	P370+P380+P375 In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313 If eye irritation persists: Get medical advice/attention. P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse.
Storage	P403 Store in a well-ventilated place. P410 Protect from sunlight. P411 Store at temperatures not exceeding …°C/…°F. P420 Store separately.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest.

In case of skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap.

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

CONTACT WITH EYES OR SKIN: irritates eyes. Prolonged contact may irritate skin. (USCG, 1999)

Excerpt from ERG Guide 145 [Organic Peroxides (Heat and Contamination Sensitive)]: Fire may produce irritating, corrosive and/or toxic gases. Ingestion or contact (skin, eyes) with substance may cause severe injury or burns. Runoff from fire control or dilution water may cause pollution. (ERG, 2016)

Excerpt from ERG Guide 146 [Organic Peroxides (Heat, Contamination and Friction Sensitive)]: Fire may produce irritating, corrosive and/or toxic gases. Ingestion or contact (skin, eyes) with substance may cause severe injury or burns. Runoff from fire control or dilution water may cause pollution. (ERG, 2016)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

For immediate first aid: Ensure that adequate decontamination has been carried out. If victim is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep victim quiet and maintain normal body temperature. Obtain medical attention. /Organic peroxides/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

If material on fire or involved in fire: Burns with explosive violence. If it becomes ignited, material cannot be extinguished until it is consumed. /Benzoyl peroxide (benzoyl peroxide, dry or wet with less than 30% water)/

5.2 Specific hazards arising from the chemical

Special Hazards of Combustion Products: Suffocating smoke evolved Behavior in Fire: May explode (USCG, 1999)

Excerpt from ERG Guide 145 [Organic Peroxides (Heat and Contamination Sensitive)]: May explode from heat or contamination. May ignite combustibles (wood, paper, oil, clothing, etc.). May be ignited by heat, sparks or flames. May burn rapidly with flare-burning effect. Containers may explode when heated. Runoff may create fire or explosion hazard. (ERG, 2016)

Excerpt from ERG Guide 146 [Organic Peroxides (Heat, Contamination and Friction Sensitive)]: May explode from heat, shock, friction or contamination. May ignite combustibles (wood, paper, oil, clothing, etc.). May be ignited by heat, sparks or flames. May burn rapidly with flare-burning effect. Containers may explode when heated. Runoff may create fire or explosion hazard. (ERG, 2016)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Evacuate danger area! Remove all ignition sources. Wash away remainder with plenty of water. Do NOT absorb in saw-dust or other combustible absorbents.

6.3 Methods and materials for containment and cleaning up

Cover the spill with a 1:1:1 mixture by weight of sodium carbonate or calcium carbonate, clay cat litter (bentonite) and sand. Dampen this mixture thoroughly with water, then scoop into a beaker using a plastic or cardboard shovel. Treat as per waste disposal procedure. Wash the area of the spill thoroughly with soap and water.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Fireproof. Separated from combustible substances and reducing agents. Store only in original packaging. See Chemical Dangers.All precautions must be taken to guard against fire and explosion hazards. Keep in a cool place out of direct rays of the sun; away from sparks, open flames and other sources of heat; away from shock, rough handling, friction from grinding, etc. Isolated storage is required; keep away from possible contact with acids, alcohols, ethers or other reducing agents or polymerization catalysts such as dimethylaniline. Complete instructions on storage and handling available from manufacturer.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 5 mg/cu m.

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

VERY STABLE /SRP: SHELF LIFE/ @ ORDINARY TEMP (25 DEG C)

10.3 Possibility of hazardous reactions

Unstable to heat; decomposes with evolving oxygen, resulting in advancing fire. Sensitive to impact and friction.BENZOYL PEROXIDE is a white, odorless powder, moderately toxic. It is most dangerous when it contains less then 1% water. A moisture content of 3% allowed slow burning only, and at 5% ignition did not occur [McCloskey, C. M. et al., Chem. Abs., 1967, 66, 12613c]. Mixed with a large surplus of water (30% or more), it is relatively safe. In dry form, it is a very dangerous material. It will explode spontaneously when heated above melting point (103° C). An explosion which occurred when a screw-capped bottle of the peroxide was opened has been attributed to friction, which initiated a mixture of peroxide and organic dust in the cap threads [Lappin, G. R., Chem. Eng. News, 1948, 26, p.3518]. A violent explosion occurred during purification of the peroxide by Soxhlet extraction with hot chloroform [Anon., Sichere Chemiearb., 1976, 28, p. 49]. It is a powerful oxidizer, which ignites readily and burns rapidly. In contact with reducing agents, it may ignite by spontaneous chemical reaction. It must be kept in a cool place, in isolation and out of the sunlight or sources of heat. Also, avoid shock or friction. It reacts violently with inorganic or organic acids, alcohols, amines, metallic naphthenates and polymerization accelerators (e.g., N,N-dimethylaniline). Explosive or violent reaction upon contact with dimethyl sulfide, lithium aluminum hydride or aniline [Bretherick, 5th ed., 1995, p. 1140]. Mixture with carbon tetrachloride and ethylene explodes when exposed to heat [Bolt, R. O. et al., Chem. Eng. News, 1947, 25, p. 1866]. Ignition occurred upon contact with methyl methacrylate [MCA Case History No. 996], polymerization of vinyl acetate in ethyl acetate accelerated out of control leading to ignition and explosion [Vervalin, 1973, p. 81]. At 50° C a mixture of dibenzoyl peroxide and charcoal reacts violently producing dense white smoke of benzoic acid, benzene, phenyls and carbon dioxide [Leleu, Cahiers, 1980, 99, p. 279].

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Special care must be taken to avoid contamination with combustible materials (wood, paper), various inorganic & organic acids, alkalies, alcohols, amines, easily oxidizable materials such as ethers, or materials used as accelerators in polymerization reactions.

10.6 Hazardous decomposition products

Explosive decomposition above the melting point ... forms flammable products.

11.Toxicological information

Acute toxicity

• Oral: LD50 Rat oral 7710 mg/kg
• Inhalation: no data available
• Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Evaluation: There is inadequate evidence in humans for the carcinogenicity of benzoyl peroxide. There is limited evidence in experimental animals for the carcinogenicity of benzoyl peroxide. Overall evaluation: Benzoyl peroxide is not classifiable as to its carcinogenicity to humans (Group 3).

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

• Toxicity to fish: no data available
• Toxicity to daphnia and other aquatic invertebrates: no data available
• Toxicity to algae: no data available
• Toxicity to microorganisms: no data available

12.2 Persistence and degradability

In the Japanese MITI test, benzoyl peroxide (present at 100 ppm) reached 84 percent of its theoretical BOD in 21 days, using an activated sludge inoculum(1).

12.3 Bioaccumulative potential

An estimated BCF of 250 was calculated for benzoyl peroxide(SRC), using an experimental log Kow of 3.46(1,SRC) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF suggests that bioconcentration in aquatic organisms is high(SRC).

12.4 Mobility in soil

The Koc of benzoyl peroxide is estimated as approximately 1,800(SRC), using a measured log Kow of 3.46(1) and a regression-derived equation(2,SRC). According to a recommended classification scheme(3), this estimated Koc value suggests that benzoyl peroxide is expected to have low mobility in soil(SRC).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

14.2 UN Proper Shipping Name

14.3 Transport hazard class(es)

14.4 Packing group, if applicable

14.5 Environmental hazards

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

16.Other information

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.