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Creatine phosphate disodium salt

CAS No.: 922-32-7
Formula: C4H11N3NaO5P
Molecular Weight: 235.11
Suppliers: All(0) China Suppliers(6) Products(9)
  • Description
  • Basic Info
  • Safety Info
  • MSDS
  • Price
  • Related Product
  • Supplier Reference
What is Creatine phosphate disodium salt

**Introduction to Creatine Phosphate Disodium Salt** Creatine phosphate disodium salt is a high-purity biochemical compound widely used in research, pharmaceuticals, and sports nutrition. As a stable form of creatine phosphate, it serves as a critical energy source for muscle and nerve tissues by rapidly regenerating ATP during high-intensity activities. This compound is particularly valuable in studies related to cellular metabolism, ischemia-reperfusion injury, and muscle performance enhancement. In pharmaceuticals, it supports cardiac and neurological therapies by improving energy metabolism under stress conditions. Additionally, it is explored in sports supplements for boosting endurance and recovery. With its excellent solubility and stability, creatine phosphate disodium salt is a versatile and essential tool in both scientific and clinical applications.

Preparation Process: The preparation of creatine phosphate disodium salt involves the following steps: 1. **Reaction**: Creatine is reacted with phosphorus oxychloride (POCl₃) in an alkaline aqueous solution (pH 9–10) to form creatine phosphate. 2. **Neutralization**: The reaction mixture is neutralized with sodium hydroxide (NaOH) to obtain the disodium salt. 3. **Purification**: The crude product is purified via recrystallization from water or ethanol-water mixtures. 4. **Drying**: The purified crystals are filtered and dried under vacuum to yield creatine phosphate disodium salt. 5. **Analysis**: The final product is characterized by HPLC, NMR, and elemental analysis to confirm purity.

Usage Scenarios: Creatine phosphate disodium salt is primarily used as a high-energy phosphate donor in biochemical and physiological research to study cellular energy metabolism, particularly in muscle and cardiac tissues. It serves as a rapid source of ATP regeneration, making it valuable in experiments involving muscle contraction, ischemia-reperfusion injury, and metabolic stress. The compound is also utilized in cell culture and tissue engineering to enhance energy supply in metabolically demanding conditions. Additionally, it finds applications in sports science research to investigate performance enhancement and recovery mechanisms. Its stability and solubility make it suitable for in vitro and ex vivo studies on energy-dependent processes.

Creatine phosphate disodium salt Basic Info
Chemical Name Creatine phosphate disodium salt
Synonyms CP;CREATINE PHOSPHATE DISODIUM;PHOSPHOCREATINE SODIUM SALT;SODIUM CREATINE PHOSPHATE;PHOSPHOCREATINE DISODIUM SALT;CREATINE PHOSPHATE SODIUM SALT;CREATININE PHOSPHATE DISODIUM SALT;PHOSPHOCREATINE, 2NA;PHOSPHOCREATINE, NA2;Creatine Phosphate S
CAS No. 922-32-7
Molecular Formula C4H11N3NaO5P
Molecular Weight 235.11
PSA 149.42000
LogP -0.01310
Safely Info
RTECS -
Hazard Class -
Safety Statements 22-24/25-36-26
HS Code 29252900
WGK Germany 3
Packing Group -
RIDADR -
Risk Statements 20/21/22-36/37/38
Hazard Codes Xn
Caution Statement P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362
Hazard Declaration H335-H332-H302-H319-H312-H315
Symbol GHS07
Signal Word Warning
Creatine phosphate disodium salt Price
Here is a rough price range for "Creatine phosphate disodium salt" in the listed countries. Note that prices can vary based on supplier, quantity, and purity, and some countries may not have readily available data:

1. **United States**: $50 - $200 per gram
2. **China**: $20 - $100 per gram
3. **Russia**: $30 - $150 per gram
4. **Germany**: $50 - $250 per gram
5. **India**: $10 - $80 per gram
6. **Japan**: $60 - $300 per gram
7. **Brazil**: $40 - $180 per gram
8. **South Korea**: $50 - $250 per gram
9. **Philippines**: No results
10. **United Kingdom**: $50 - $250 per gram
11. **France**: $50 - $250 per gram
12. **Mexico**: $30 - $150 per gram
13. **Canada**: $50 - $200 per gram
14. **South Africa**: $40 - $180 per gram
15. **Egypt**: No results
16. **Turkey**: $30 - $150 per gram
17. **Thailand**: $20 - $100 per gram
18. **Indonesia**: No results

These ranges are approximate and based on general market trends. Prices may vary significantly depending on the supplier and specific requirements.
MSDS
MSDS
Name: Creatine Phosphate Disodium Salt Tetrahydrate 99% Material Safety Data Sheet
Synonym: Phosphocreatine Disodium Salt
CAS: 922-32-7
Section 1 - Chemical Product   MSDS Name:Creatine Phosphate Disodium Salt Tetrahydrate 99% Material Safety Data Sheet
Synonym:Phosphocreatine Disodium Salt

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
922-32-7 Creatine Phosphate Disodium Salt Tetra 99% 213-074-6
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.) Store under an inert atmosphere.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 922-32-7: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Powder
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: soluble in water
Specific Gravity/Density:
Molecular Formula: C4H8N3Na2O5P.4H2O
Molecular Weight: 327.14

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, oxides of phosphorus, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 922-32-7 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Creatine Phosphate Disodium Salt Tetrahydrate - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 922-32-7: 1
Canada
CAS# 922-32-7 is listed on Canada's NDSL List.
CAS# 922-32-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 922-32-7 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
SDS 1.0
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