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Poly(ethylene glycol-ran-propylene glycol) monobutyl ether

CAS No.: 9038-95-3
Formula: C9H20O3
Molecular Weight: 176.26
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What is Poly(ethylene glycol-ran-propylene glycol) monobutyl ether

Poly(ethylene glycol-ran-propylene glycol) monobutyl ether is a block copolymer that consists of a hydrophilic poly(ethylene glycol) (PEG) segment and a hydrophobic poly(propylene glycol) (PPO) segment. One of the significant features of PEG-PPO monobutyl ether is its amphiphilic nature. This means that it has both hydrophilic and hydrophobic regions within its structure. This property allows PEG-PPO monobutyl ether to form micelles in aqueous solutions, where the hydrophobic PPO segments aggregate in the core while the hydrophilic PEG segments form the outer shell. The formation of micelles gives PEG-PPO monobutyl ether its surfactant properties. In pharmaceuticals, it is utilized as an excipient in drug formulations to improve solubility, stability, and controlled release of drugs. It can also be employed as a carrier for drug delivery systems, enhancing the bioavailability and targeting of therapeutic agents. Furthermore, PEG-PPO monobutyl ether finds applications in cosmetics as an emulsifier and solubilizer for various formulations. The mechanism of action of PEG-PPO monobutyl ether relies on its ability to self-assemble into micelles in aqueous solutions. When added to a system, the hydrophobic PPO segments aggregate together, forming a core, while the hydrophilic PEG segments create a protective shell around the core. This self-assembly process enables PEG-PPO monobutyl ether to solubilize hydrophobic substances and stabilize emulsions. It can also enhance the penetration and absorption of drugs through biological membranes.

Poly(ethylene glycol-ran-propylene glycol) monobutyl ether Basic Info
Chemical Name Poly(ethylene glycol-ran-propylene glycol) monobutyl ether
Synonyms Toximul 8320;PPG-12-BUTETH-12;PPG-12-BUTETH-16;u-660;u-2000;u-5100;PPG-28;TERGITOL XD;TERGITOL XH;UCON HB1500
CAS No. 9038-95-3
Molecular Formula C9H20O3
Molecular Weight 176.26
PSA -
LogP -
Safely Info
RTECS YP8450000
Hazard Class -
Safety Statements 26-36/37/39
HS Code -
WGK Germany -
Packing Group -
RIDADR UN 3082 9/PG 3
Risk Statements 20/21/22-38-41
Hazard Codes Xn,N
Caution Statement P261-P271-P304+P340-P312
Hazard Declaration H332
Symbol GHS07
Signal Word Warning
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