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L(+)-Lactic acid

CAS No.: 79-33-4
Formula: C3H6O3
Molecular Weight: 90.08
Suppliers: All(0) China Suppliers(0) Products(16)
  • Description
  • Basic Info
  • Safety Info
  • MSDS
  • Price
  • Related Product
  • Supplier Reference
What is L(+)-Lactic acid

**(S)-Lactic Acid: A High-Purity Biochemical** (S)-Lactic acid, also known as L-lactic acid, is a chiral organic acid widely used in food, pharmaceutical, and cosmetic industries. As the biologically active enantiomer, it plays a key role in metabolic processes and serves as a critical intermediate in biodegradable polymers like polylactic acid (PLA). Its high purity and biocompatibility make it ideal for medical applications, including drug delivery and surgical sutures. Additionally, (S)-lactic acid is valued in skincare for its exfoliating and moisturizing properties. Produced via microbial fermentation, it offers a sustainable alternative to petroleum-based chemicals, aligning with green chemistry principles. Its versatility and eco-friendly profile make it indispensable in modern industrial and biomedical applications.

Preparation Process: To prepare (S)-lactic acid, ferment glucose or other sugars using *Lactobacillus* bacteria, which selectively produce the (S)-enantiomer. Alternatively, chemically synthesize racemic lactic acid (DL-lactic acid) via hydrolysis of lactonitrile or oxidation of propylene glycol, then resolve the enantiomers. Enzymatic resolution employs lipases or esterases to selectively hydrolyze one enantiomer from a racemic ester. Another method is asymmetric synthesis using chiral catalysts, such as Jacobsen’s catalyst, to hydrogenate pyruvic acid or its derivatives enantioselectively. Purify the product via crystallization, distillation, or chromatography. Ensure optical purity by polarimetry or chiral HPLC analysis.

Usage Scenarios: (S)-Lactic acid, or L-lactic acid, is widely used in the food industry as a preservative, acidulant, and flavor enhancer. In pharmaceuticals, it serves as a pH adjuster and in topical formulations for skin exfoliation. It is a key component in biodegradable polymers, such as polylactic acid (PLA), used in eco-friendly packaging and medical implants. In cosmetics, it acts as a moisturizer and anti-aging agent due to its humectant and exfoliating properties. Additionally, (S)-lactic acid is employed in chemical synthesis, textile dyeing, and leather processing. Its biocompatibility makes it valuable in biomedical applications, including drug delivery systems and tissue engineering scaffolds.

L(+)-Lactic acid Basic Info
Chemical Name L(+)-Lactic acid
Synonyms L-LACTIC ACID;2-HYDROXYPROPIONIC ACID;LACTIC ACI;Lactic acid, L-;SARCOLACTIC ACID;ph90;Tisulac;Espiritin;HiPure 90;PURAC(R) 50
CAS No. 79-33-4
Molecular Formula C3H6O3
Molecular Weight 90.08
PSA 57.53000
LogP -0.54820
Safely Info
RTECS OD2800000
Hazard Class 8
Safety Statements 26-39-45-36/37/39-36
HS Code 29181100
WGK Germany 1
Packing Group III
RIDADR 3261
Risk Statements 38-41-34-36/37/38-36-35
Hazard Codes Xi,C
Caution Statement P264-P280-P302+P352-P305+P351+P338-P332+P313-P362+P364
Hazard Declaration H315-H318
Symbol GHS05
Signal Word Danger
L(+)-Lactic acid Price
Here is a rough price range for (S)-lactic acid in the 18 countries listed. Note that prices can vary based on purity, quantity, and supplier, and some countries may not have readily available data:

1. **United States**: $20 - $50 per kg
2. **China**: $10 - $30 per kg
3. **Russia**: $25 - $60 per kg
4. **Germany**: $30 - $70 per kg
5. **India**: $15 - $40 per kg
6. **Japan**: $40 - $80 per kg
7. **Brazil**: $20 - $50 per kg
8. **South Korea**: $35 - $75 per kg
9. **Philippines**: No results
10. **United Kingdom**: $30 - $70 per kg
11. **France**: $30 - $70 per kg
12. **Mexico**: $20 - $50 per kg
13. **Canada**: $25 - $60 per kg
14. **South Africa**: No results
15. **Egypt**: No results
16. **Turkey**: $25 - $60 per kg
17. **Thailand**: $20 - $50 per kg
18. **Indonesia**: No results

These ranges are approximate and may not reflect current market conditions. Prices can vary significantly depending on the supplier and specific requirements.
MSDS
MSDS
Name: L-(+)-Lactic Acid 90% Material Safety Data Sheet
Synonym: (S)-(+)-2-Hydroxypropanoic Acid, (S)-Lactic Acid; (S)-(+)-Lactic Acid
CAS: 79-33-4
Section 1 - Chemical Product   MSDS Name:L-(+)-Lactic Acid 90% Material Safety Data Sheet
Synonym:(S)-(+)-2-Hydroxypropanoic Acid, (S)-Lactic Acid; (S)-(+)-Lactic Acid

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
79-33-4 L-(+)-LACTIC ACID 90.0 201-196-2
Hazard Symbols: C
Risk Phrases: 34

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Causes burns.Corrosive.
Potential Health Effects
Eye:
Causes eye burns. Causes redness and pain. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes skin burns. Causes redness and pain.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract. May cause systemic effects.
Chronic:
Chronic exposure may cause effects similar to those of acute exposure.

Section 4 - FIRST AID MEASURES
  Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode when heated.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid ingestion and inhalation. Do not ingest or inhale. Wash clothing before reuse.
Discard contaminated shoes.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Store protected from moisture.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 79-33-4: CAS# 97-73-4: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Liquid
Color: almost colorless
Odor: Characteristic odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: mPas 25 deg C
Boiling Point: 119 deg C
Freezing/Melting Point: 53 deg C
Autoignition Temperature: Not available.
Flash Point: > 112 deg C (> 233.60 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >200 deg C
Solubility in water: Soluble.
Specific Gravity/Density: 1.2060g/cm3
Molecular Formula: C3H6O3
Molecular Weight: 90.08

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions. Hygroscopic: absorbs moisture or water from the air.
Conditions to Avoid:
Ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong bases, strong oxidizing agents, strong reducing agents, metals.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 79-33-4: OD3100000 CAS# 97-73-4 unlisted.
LD50/LC50:
Not available.
Not available.
Carcinogenicity:
L-(+)-LACTIC ACID - Not listed by ACGIH, IARC, or NTP.
Lactic Anhydride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Ecotoxicity:
Fish: Pseudomonas putida:

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.*
Hazard Class: 8
UN Number: 3265
Packing Group: III
IMO
Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3265
Packing Group: III
RID/ADR
Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3265
Packing group: III

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 79-33-4: 0
CAS# 97-73-4: No information available.
Canada
CAS# 79-33-4 is listed on Canada's DSL List.
CAS# 97-73-4 is listed on Canada's NDSL List.
CAS# 79-33-4 is not listed on Canada's Ingredient Disclosure List.
CAS# 97-73-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 79-33-4 is listed on the TSCA inventory.
CAS# 97-73-4 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A
SDS 1.0
L(+)-Lactic acid Suppliers
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China Hunan Changsha
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China Henan Zhengzhou
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China Shandong Jinan
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China Hebei Shijiazhuang
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