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ALLERGEN GAL D 4 (46-61) (CHICKEN)

CAS No.: 62982-31-4

Formula: C72H116N22O29

Molecular Weight: 1753.82

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What is ALLERGEN GAL D 4 (46-61) (CHICKEN)

**Introduction to ALLERGEN GAL D 4 (46-61) (CHICKEN)** ALLERGEN GAL D 4 (46-61) is a synthetic peptide fragment derived from chicken serum albumin (Gal d 4), a known allergen in poultry. This specific sequence (residues 46-61) plays a key role in IgE-mediated allergic responses, making it valuable for research and diagnostic applications. Scientists use this peptide to study allergenicity mechanisms, develop allergy tests, and explore potential immunotherapies. Its well-defined structure ensures consistency in experiments, aiding in the investigation of cross-reactivity with other avian allergens. Ideal for immunological studies, ALLERGEN GAL D 4 (46-61) supports advancements in understanding and managing chicken-related allergies, benefiting both clinical and research settings.

Preparation Process: To prepare **ALLERGEN GAL D 4 (46-61) (CHICKEN)**, follow these steps: 1. **Solid-Phase Peptide Synthesis (SPPS)**: Use Fmoc chemistry to assemble the peptide sequence (46-61) of chicken lysozyme allergen Gal d 4 on a resin. 2. **Deprotection & Coupling**: Remove Fmoc groups with piperidine and couple amino acids using HBTU/HOBt/DIPEA. 3. **Cleavage**: Treat the resin with TFA/TIS/water (95:2.5:2.5) to release the peptide. 4. **Purification**: Purify via reversed-phase HPLC (C18 column, acetonitrile/water gradient). 5. **Lyophilization**: Freeze-dry the purified peptide. 6. **Characterization**: Confirm identity using mass spectrometry and analytical HPLC. Store at -20°C. (Word count: 100)

Usage Scenarios: ALLERGEN GAL D 4 (46-61) (CHICKEN) is a peptide fragment derived from chicken egg lysozyme, a known allergen. It is primarily used in immunological research to study allergic responses, particularly IgE-mediated hypersensitivity. Scientists employ this compound to investigate epitope specificity, cross-reactivity, and immune mechanisms in egg allergies. It aids in developing diagnostic tools, such as allergy tests, to identify sensitization in patients. Additionally, it supports the design of hypoallergenic food products and potential immunotherapies. The peptide helps elucidate molecular interactions between allergens and antibodies, contributing to advancements in allergy prevention and treatment strategies. Its synthetic nature ensures consistency in experimental studies.

ALLERGEN GAL D 4 (46-61) (CHICKEN) Basic Info

Chemical Name ALLERGEN GAL D 4 (46-61) (CHICKEN)

Synonyms HEL (46-61);GAL D IV (46-61) (CHICKEN);LYSOZYME C (46-61) (CHICKEN);hen egg lysozyme peptide (46-61);ALLERGEN GAL D 4 (46-61) (CHICKEN);1,4-BETA-N-ACETYLMURAMIDASE C (46-61) (CHICKEN);HEL (46-61),Lysozyme C (46-61) (chicken) trifluoroacetate salt;H-ASN-THR-ASP-GLY-SER-THR-ASP-TYR-GLY-ILE-LEU-GLN-ILE-ASN-SER-ARG-OH;Gal d IV (46-61) (chicken), Allergen Gal d 4 (46-61) (chicken), 1,4-b-N-AcetylMuraMidase C (46-61) (chicken);Lysozyme C (46-61) (chicken)/Allergen Gal d 4 (46-61) (chicken), Gal d IV (46-61) (chicken), 1,4-β-N-Acetylmuramidase C (46-61) (chicken)

CAS No. 62982-31-4

Molecular Formula C72H116N22O29

Molecular Weight 1753.82

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ALLERGEN GAL D 4 (46-61) (CHICKEN) Price

1. United States: $50 - $150
2. China: $30 - $100
3. Russia: $40 - $120
4. Germany: $60 - $160
5. India: $20 - $80
6. Japan: $70 - $180
7. Brazil: $35 - $110
8. South Korea: $50 - $140
9. Philippines: $25 - $90
10. United Kingdom: $55 - $150
11. France: $60 - $170
12. Mexico: $30 - $100
13. Canada: $50 - $160
14. South Africa: $25 - $90
15. Egypt: $20 - $80
16. Turkey: $30 - $100
17. Thailand: $25 - $90
18. Indonesia: $20 - $80

Note: These are rough estimates and may vary based on availability, supplier, and market conditions. If no specific data is available, the ranges are based on general trends for similar products.