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Sucrose octaacetate

CAS No.: 126-14-7
Formula: C28H38O19
Molecular Weight: 678.59
Suppliers: All(0) China Suppliers(0) Products(5)
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  • Basic Info
  • Safety Info
  • MSDS
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What is Sucrose octaacetate

**Introduction to Sucrose Octaacetate** Sucrose octaacetate (SOA) is a chemically modified derivative of sucrose in which all eight hydroxyl groups are acetylated. This white, crystalline solid is known for its intensely bitter taste, making it a valuable non-toxic additive in denaturing ethanol, deterring ingestion in industrial and laboratory settings. Additionally, SOA serves as an intermediate in organic synthesis, particularly in pharmaceuticals and agrochemicals. Its stability and low solubility in water enhance its utility in coatings and specialty chemicals. With applications ranging from aversive agents to biodegradable plasticizers, sucrose octaacetate combines versatility with safety, offering a functional solution across multiple industries.

Preparation Process: Sucrose octaacetate is prepared by acetylating sucrose with acetic anhydride in the presence of a catalyst. Typically, sucrose is dissolved in pyridine, and acetic anhydride is added dropwise under stirring at room temperature. The reaction is exothermic, so cooling may be required. After complete addition, the mixture is stirred for several hours to ensure full acetylation. The product is then precipitated by pouring the reaction mixture into ice-cold water, filtered, and washed thoroughly to remove residual reagents. Recrystallization from ethanol or methanol yields pure sucrose octaacetate as a white crystalline solid. The process ensures all eight hydroxyl groups of sucrose are acetylated.

Usage Scenarios: Sucrose octaacetate (SOA) is primarily used as a bittering agent due to its intensely bitter taste, making it valuable in denaturing alcohol, deterring ingestion of toxic substances, and as an aversive additive in products like antifreeze and nail polish to prevent accidental consumption. In pharmaceuticals, it serves as a non-toxic bitter excipient in oral medications to discourage misuse, especially in pediatric formulations. SOA is also employed in chemical research as a precursor for synthesizing other sucrose derivatives. Additionally, it finds applications in coatings, adhesives, and plastics as a modifying agent due to its acetylated structure, enhancing material properties.

Sucrose octaacetate Basic Info
Chemical Name Sucrose octaacetate
Synonyms Soa;FEMA 3038;SUCROSE OCTACETATE;Octa D;aacetate;204-772-1;bitter taste;OCTAACETYLSUCROSE;Sucrose octa actate;Sucrose octaacetate
CAS No. 126-14-7
Molecular Formula C28H38O19
Molecular Weight 678.59
PSA 238.09000
LogP -0.82920
Safely Info
RTECS WN6620000
Hazard Class -
Safety Statements 24/25-37/39-26
HS Code 29400090
WGK Germany 2
Packing Group -
RIDADR -
Risk Statements 36/37/38
Hazard Codes Xi
Caution Statement -
Hazard Declaration -
Symbol -
Signal Word -
Sucrose octaacetate Price
United States: $50-100
China: $30-60
Russia: $40-80
Germany: $60-100
India: $20-40
Japan: $70-120
Brazil: $30-60
South Korea: $40-80
Philippines: No results
United Kingdom: $50-90
France: $60-100
Mexico: $30-60
Canada: $50-90
South Africa: $20-40
Egypt: $25-45
Turkey: $30-60
Thailand: $25-50
Indonesia: $20-40
MSDS
MSDS
Name: Sucrose Octaacetate 98.0-100.5% (on Dry Substance) Material Safety Data Sheet
Synonym: Alpha-D-Glucopyranoside; Octaacetylsucrose
CAS: 126-14-7
Section 1 - Chemical Product   MSDS Name:Sucrose Octaacetate 98.0-100.5% (on Dry Substance) Material Safety Data Sheet
Synonym:Alpha-D-Glucopyranoside; Octaacetylsucrose

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
126-14-7 Sucrose Octaacetate >98 204-772-1
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Hygroscopic (absorbs moisture from the air).The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. The toxicological properties of this material have not been fully investigated.
Skin:
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Do NOT get water inside containers. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation. Do not get water inside containers.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Do not allow contact with water. Keep from contact with moist air and steam.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 126-14-7: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Crystalline powder
Color: white
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: P 100 deg C
Boiling Point: 250 deg C @ 1.00mm Hg
Freezing/Melting Point: 78 - 85 deg C
Autoignition Temperature: Not available.
Flash Point: 285 deg C ( 545.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 285 deg C
Solubility in water: soluble in acetic acid, acetone, benzene
Specific Gravity/Density: 1.2800g/cm3
Molecular Formula: C28H38O19
Molecular Weight: 678.59

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, moisture, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 126-14-7: WN6620000 LD50/LC50:
CAS# 126-14-7: Draize test, rabbit, skin: 500 mg/24H Mild; Oral, rat: LD50 = >5 gm/kg; Skin, rabbit: LD50 = >5 gm/kg.
Carcinogenicity:
Sucrose Octaacetate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 126-14-7: No information available.
Canada
CAS# 126-14-7 is listed on Canada's DSL List.
CAS# 126-14-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 126-14-7 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A
SDS 1.0
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