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polyethylene glycol hydroxystearate

CAS No.: 1192130-70-3

Formula: C20H40O4

Molecular Weight: 344.52900

Suppliers: All(0) China Suppliers(0) Products(0)

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What is polyethylene glycol hydroxystearate

**Introduction to Polyethylene Glycol Hydroxystearate** Polyethylene glycol hydroxystearate (PEG hydroxystearate) is a nonionic surfactant and emulsifier widely used in pharmaceuticals, cosmetics, and personal care products. Derived from hydroxystearic acid and polyethylene glycol (PEG), it enhances solubility, stability, and texture in formulations. Its amphiphilic nature allows it to improve the dispersion of oils in water, making it ideal for creams, lotions, and ointments. Additionally, PEG hydroxystearate is valued for its mildness, making it suitable for sensitive skin applications. In pharmaceuticals, it serves as an excipient to improve drug delivery and bioavailability. Its versatility, safety, and compatibility with various ingredients make it a key component in modern formulations.

Preparation Process: Polyethylene glycol hydroxystearate is synthesized by esterifying hydroxystearic acid with polyethylene glycol (PEG). First, hydroxystearic acid and PEG (selected molecular weight, e.g., PEG-400 or PEG-600) are mixed in a molar ratio of 1:1 to 1:2. A catalyst, such as p-toluenesulfonic acid or sulfuric acid (0.5–1% w/w), is added. The reaction occurs at 110–130°C under nitrogen atmosphere to prevent oxidation. Water formed during esterification is removed via azeotropic distillation or vacuum. After 4–6 hours, the mixture is cooled, neutralized with a base (e.g., sodium bicarbonate), and purified by washing with water or solvent extraction. The product is dried under vacuum to yield the final compound.

Usage Scenarios: Polyethylene glycol hydroxystearate (PEG hydroxystearate) is a nonionic surfactant widely used in pharmaceuticals, cosmetics, and personal care products. It acts as an emulsifier, solubilizer, and stabilizer, enhancing the dispersion of oils in water-based formulations. In pharmaceuticals, it improves drug solubility and bioavailability in oral and topical preparations. In cosmetics, it helps blend ingredients in creams, lotions, and sunscreens while ensuring smooth texture and stability. Its mild nature makes it suitable for sensitive skin applications. Additionally, PEG hydroxystearate is used in industrial applications, such as lubricants and coatings, due to its surfactant and wetting properties.

polyethylene glycol hydroxystearate Basic Info

Chemical Name polyethylene glycol hydroxystearate

Synonyms glycol hydroxystearate

CAS No. 1192130-70-3

Molecular Formula C20H40O4

Molecular Weight 344.52900

PSA 66.76000

LogP 4.75420

polyethylene glycol hydroxystearate Price

Here is a rough price range for polyethylene glycol hydroxystearate in the listed countries. Note that prices can vary based on quantity, supplier, and market conditions:

1. **United States**: $10 - $50 per kg
2. **China**: $5 - $30 per kg
3. **Russia**: $8 - $40 per kg
4. **Germany**: $12 - $60 per kg
5. **India**: $6 - $35 per kg
6. **Japan**: $15 - $70 per kg
7. **Brazil**: $10 - $45 per kg
8. **South Korea**: $12 - $55 per kg
9. **Philippines**: No results
10. **United Kingdom**: $12 - $65 per kg
11. **France**: $12 - $60 per kg
12. **Mexico**: $8 - $40 per kg
13. **Canada**: $10 - $50 per kg
14. **South Africa**: $10 - $45 per kg
15. **Egypt**: No results
16. **Turkey**: $8 - $40 per kg
17. **Thailand**: $7 - $35 per kg
18. **Indonesia**: $6 - $30 per kg

Prices are approximate and may vary significantly depending on the supplier, purity, and market conditions.