Squalane C30H62 Properties,Formula,Price, Uses

What is Squalane

Squalane is a lightweight, non-greasy, and highly versatile skincare ingredient derived from renewable plant sources such as olives, sugarcane, or rice bran. Known for its exceptional moisturizing properties, squalane mimics the skin’s natural lipids, helping to restore hydration, improve elasticity, and strengthen the skin’s moisture barrier. It is suitable for all skin types, including sensitive and acne-prone skin, as it is non-comedogenic and easily absorbed. Rich in antioxidants, squalane also helps protect the skin from environmental stressors and free radicals, promoting a smoother, more radiant complexion. Its gentle yet effective formula makes it a popular choice for serums, moisturizers, and oils, offering a natural solution for healthy, hydrated skin.

Preparation Process: Squalane is prepared through the hydrogenation of squalene, a natural triterpene found in shark liver oil or plant sources like olive oil. The process involves catalytic hydrogenation under high pressure (typically 5–30 atm) using a palladium or nickel catalyst at 80–120°C. The reaction saturates squalene's six double bonds, converting it into fully saturated squalane. The crude product is then purified via distillation or chromatography to remove residual catalysts and byproducts. Alternatively, squalane can be synthesized from sugarcane-derived farnesene via oligomerization and hydrogenation. The final product is a colorless, odorless, and stable hydrocarbon used in cosmetics and pharmaceuticals.

Usage Scenarios: Squalane is a saturated hydrocarbon derived from squalene, commonly used in skincare and cosmetic products due to its excellent moisturizing and emollient properties. It mimics the skin’s natural lipids, enhancing hydration and improving skin barrier function. Lightweight and non-greasy, squalane is suitable for all skin types, including sensitive and acne-prone skin. It helps reduce dryness, fine lines, and irritation while promoting a smooth, supple texture. Additionally, squalane acts as an antioxidant, protecting the skin from environmental damage. It is often found in serums, moisturizers, and haircare products to add shine and reduce frizz. Its stability and biocompatibility make it a preferred ingredient in formulations.

Squalane Basic Info

Chemical Name Squalane

Synonyms ROBANE;Synthetic squalane;Dermane;Dodecahydrosqualene;2,6,10,15,19,23-HEXAMETHYLTETRACOSANE;Romane;COSBIOL;Squalan;SQUALANE;SPINACANE

CAS No. 111-01-3

Molecular Formula C30H62

Molecular Weight 422.81

PSA 0.00000

LogP 11.08440

Safely Info

RTECS XB6070000

Hazard Class -

Safety Statements 26-36

HS Code 29012990

WGK Germany 3

Packing Group -

RIDADR -

Risk Statements 36/37/38

Hazard Codes Xi

Caution Statement P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Declaration H315-H319-H335

Symbol GHS07

Signal Word Warning

Squalane Price

Here is a rough price range for Squalane in the 18 countries listed. Note that prices can vary based on purity, source (e.g., plant-based or shark-derived), and quantity. If no specific data is available, it is marked as "No results":

1. **United States**: $20 - $50 per 100ml
2. **China**: $15 - $40 per 100ml
3. **Russia**: $25 - $60 per 100ml
4. **Germany**: $30 - $70 per 100ml
5. **India**: $10 - $30 per 100ml
6. **Japan**: $40 - $80 per 100ml
7. **Brazil**: $20 - $50 per 100ml
8. **South Korea**: $35 - $75 per 100ml
9. **Philippines**: $15 - $40 per 100ml
10. **United Kingdom**: $30 - $70 per 100ml
11. **France**: $35 - $75 per 100ml
12. **Mexico**: $20 - $50 per 100ml
13. **Canada**: $25 - $60 per 100ml
14. **South Africa**: $20 - $50 per 100ml
15. **Egypt**: No results
16. **Turkey**: $15 - $40 per 100ml
17. **Thailand**: $10 - $35 per 100ml
18. **Indonesia**: $10 - $30 per 100ml

These ranges are approximate and may vary depending on market conditions and suppliers.

MSDS

Name:	Squalane 99% Material Safety Data Sheet
Synonym:	2,6,10,15,19,23-Hexamethyltetracosan
CAS:	111-01-3

Section 1 - Chemical Product MSDS Name:Squalane 99% Material Safety Data Sheet
Synonym:2,6,10,15,19,23-Hexamethyltetracosan

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
111-01-3	Squalane	99	203-825-6

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. The toxicological properties of this material have not been fully investigated.
Skin:
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry place. Keep container closed when not in use.
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 111-01-3: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Color: clear almost colorless
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: 34 cP 20.00 deg C
Boiling Point: 176 deg C @ .05mmHg
Freezing/Melting Point: -38 deg C
Autoignition Temperature: Not available.
Flash Point: 217 deg C ( 422.60 deg F)
Explosion Limits, lower: N/A
Explosion Limits, upper: N/A
Decomposition Temperature:
Solubility in water: slightly soluble in methanol, ethanol an
Specific Gravity/Density: .8070g/cm3
Molecular Formula: C30H62
Molecular Weight: 422.82

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 111-01-3: XB6070000 LD50/LC50:
CAS# 111-01-3: Draize test, rabbit, skin: 100 mg/24H Mild.
Carcinogenicity:
Squalane - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 111-01-3: 1
Canada
CAS# 111-01-3 is listed on Canada's DSL List.
CAS# 111-01-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 111-01-3 is listed on the TSCA inventory.

SECTION 16 - ADDITIONAL INFORMATION
N/A

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1.Identification

1.1 GHS Product identifier

Product name	2,6,10,15,19,23-hexamethyltetracosane

1.2 Other means of identification

Product number	-
Other names	Robane

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only. Emollients;Skin Conditioning Agents
Uses advised against	no data available

1.4 Supplier's details

Company	MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address	Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road, Xuhui District, Shanghai, China
Telephone	+86(21)64956998
Fax	+86(21)54365166

1.5 Emergency phone number

Emergency phone number	+86-400-6021-666
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Not classified.

2.2 GHS label elements, including precautionary statements

Pictogram(s)	No symbol.
Signal word	No signal word.
Hazard statement(s)	none
Precautionary statement(s)
Prevention	none
Response	none
Storage	none
Disposal	none

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name	Common names and synonyms	CAS number	EC number	Concentration
2,6,10,15,19,23-hexamethyltetracosane	2,6,10,15,19,23-hexamethyltetracosane	111-01-3	none	100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state	viscous colourless liquid
Colour	no data available
Odour	no data available
Melting point/ freezing point	235°C(lit.)
Boiling point or initial boiling point and boiling range	148°C(lit.)
Flammability	no data available
Lower and upper explosion limit / flammability limit	no data available
Flash point	217°C(lit.)
Auto-ignition temperature	no data available
Decomposition temperature	no data available
pH	no data available
Kinematic viscosity	no data available
Solubility	no data available
Partition coefficient n-octanol/water (log value)	no data available
Vapour pressure	1.45E-08mmHg at 25°C
Density and/or relative density	0.8085
Relative vapour density	no data available
Particle characteristics	no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

no data available

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

no data available

11.Toxicological information

Acute toxicity

Oral: no data available
Inhalation: no data available
Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

Toxicity to fish: no data available
Toxicity to daphnia and other aquatic invertebrates: no data available
Toxicity to algae: no data available
Toxicity to microorganisms: no data available

12.2 Persistence and degradability

no data available

12.3 Bioaccumulative potential

no data available

12.4 Mobility in soil

no data available

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN2986

IMDG: UN2986

IATA: UN2986

14.2 UN Proper Shipping Name

ADR/RID: CHLOROSILANES, CORROSIVE, FLAMMABLE, N.O.S.

IMDG: CHLOROSILANES, CORROSIVE, FLAMMABLE, N.O.S.

IATA: CHLOROSILANES, CORROSIVE, FLAMMABLE, N.O.S.

14.3 Transport hazard class(es)

ADR/RID: 8

IMDG: 8

IATA: 8

14.4 Packing group, if applicable

ADR/RID: II

IMDG: II

IATA: II

14.5 Environmental hazards

ADR/RID: no

IMDG: no

IATA: no

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name	Common names and synonyms	CAS number	EC number
2,6,10,15,19,23-hexamethyltetracosane	2,6,10,15,19,23-hexamethyltetracosane	111-01-3	none
European Inventory of Existing Commercial Chemical Substances (EINECS)			Listed.
EC Inventory			Listed.
United States Toxic Substances Control Act (TSCA) Inventory			Listed.
China Catalog of Hazardous chemicals 2015			Not Listed.
New Zealand Inventory of Chemicals (NZIoC)			Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS)			Listed.
Vietnam National Chemical Inventory			Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)			Listed.

16.Other information

Information on revision

Creation Date	Aug 10, 2017
Revision Date	Aug 10, 2017

Abbreviations and acronyms

CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%

References

IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.

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